Ethyl isonicotinate → HCID 178468862, compound

HRID 2418895Notes

Reaction equation

HRID 2418895 reaction equation
CC(C)S(=O)O.CCOC(=O)c1ccncc1.[Zn]>CC(C)(C)OO.ClCCCl.O.O=C(O)C(F)(F)F>CCOC(=O)c1cc(C(C)C)nc(C(C)C)c1.CCOC(=O)c1ccnc(C(C)C)c1

Participants

8

Reactant 2

HCID 15291Ethyl isonicotinateHCID 117778686Propane-2-sulfinic acid;ZINC

Product 2

HCID 59312761Ethyl 2-isopropylisonicotinateYield 20%HCID 178468862HCID 178468862, compoundYield 27%

Reagents, catalysts & solvents 4

HCID 6410tert-Butyl hydroperoxideReagentHCID 6422Trifluoroacetic acidReagentHCID 111,2-DichloroethaneSolventHCID 962WaterSolvent

Conditions

Temperature
50 °C

Sources & evidence

ORD record
ord-7d0af1e8b8cd4df4a01ddbc9214d4058
Source dataset
Minisci dataset from Roche

Reaction notes

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