4-Hydroxybenzaldehyde → HCID 57787712, compound

HRID 2426756Notes

Reaction equation

HRID 2426756 reaction equation
C(=O)([O-])[O-].[K+].[K+].[Cl:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([CH2:20]Cl)[CH:15]=2)=[C:10]([CH3:22])[CH:9]=1.[OH:23][C:24]1[CH:31]=[CH:30][C:27]([CH:28]=[O:29])=[CH:26][CH:25]=1>CN(C=O)C>[Cl:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([CH2:20][O:23][C:24]3[CH:31]=[CH:30][C:27]([CH:28]=[O:29])=[CH:26][CH:25]=3)[CH:15]=2)=[C:10]([CH3:22])[CH:9]=1

Participants

5

Reactant 3

HCID 1264-HydroxybenzaldehydeHCID 11430Potassium CarbonateHCID 59855123HCID 59855123, compound

Product 1

HCID 57787712HCID 57787712, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Potassium carbonate was added to a DMF solution of 4-chloro-3′-(chloromethyl)-2-methylbiphenyl and 4-hydroxybenzaldehyde, followed by stirring at room temperature for 20 hours to obtain 4-[(4′-chloro-2′-methylbiphenyl-3-yl)methoxy]benzaldehyde.

Sources & evidence

ORD record
ord-0e5cee897edf45fe9c2756331876b6dc
Source dataset
uspto-grants-2011_06
Patent number
US07968552B2

Reaction notes

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