Triethylamine → HCID 57787931, compound

HRID 2426762Notes

Reaction equation

HRID 2426762 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[OH:6][C:7]1[CH:12]=[C:11]([CH3:13])[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([CH2:20][O:21][C:22]3[CH:29]=[CH:28][C:25]([CH:26]=[O:27])=[CH:24][CH:23]=3)[CH:15]=2)=[C:9]([CH3:30])[CH:8]=1.C(N(CC)CC)C>C(OCC)(=O)C>[CH3:1][S:2]([O:6][C:7]1[CH:8]=[C:9]([CH3:30])[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([CH2:20][O:21][C:22]3[CH:23]=[CH:24][C:25]([CH:26]=[O:27])=[CH:28][CH:29]=3)[CH:15]=2)=[C:11]([CH3:13])[CH:12]=1)(=[O:4])=[O:3]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 57787477HCID 57787477, compound

Product 1

HCID 57787931HCID 57787931, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Conditions

Temperature
0 °C

Procedure

Methanesulfonyl chloride was dropwise added under ice-cooling to a mixture of 4-[(4′-hydroxy-2′,6′-dimethylbiphenyl-3-yl)methoxy]benzaldehyde, triethylamine and ethyl acetate, followed by stirring at 0° C. for 2 hours to obtain 3′-[(4-formylphenoxy)methyl]-2,6-dimethylbiphenyl-4-yl methanesulfonate.

Sources & evidence

ORD record
ord-71f8b1c3fc37457a834bd76c9720795e
Source dataset
uspto-grants-2011_06
Patent number
US07968552B2

Reaction notes

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