Triethylamine → HCID 23158638, compound

HRID 252657Notes

Reaction equation

HRID 252657 reaction equation
[SH:1][CH2:2][C:3]([O:5]CC)=O.[N:8]([CH2:11][CH2:12][S:13]([O:16][CH2:17][CH3:18])(=[O:15])=[O:14])=[C:9]=[S:10].N(CCS(O)(=O)=O)=C=S.C(N(CC)CC)C>ClCCCl>[O:5]=[C:3]1[CH2:2][S:1][C:9](=[S:10])[N:8]1[CH2:11][CH2:12][S:13]([O:16][CH2:17][CH3:18])(=[O:15])=[O:14]

Participants

6

Reactant 4

HCID 8471TriethylamineHCID 12185Ethyl ThioglycolateHCID 19008558HCID 19008558, compoundHCID 23158640HCID 23158640, compound

Product 1

HCID 23158638HCID 23158638, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

Ethyl 2-mercaptoacetate (I-A) and ethyl 2-isothiocyanato-ethanesulfonate (I-B) or 2-isothiocyanato-ethanesulfonic acid, alternatively, are dissolved in 1,2-dichloroethane and triethylamine is added. The product ethyl 2-(4-oxo-2-thioxothiazolidin-3-yl)-ethanesulfonate (1-C) can be isolated after e.g. 1 h of stirring and subsequent solvent removement.

Sources & evidence

ORD record
ord-ae2d294b728a40f0808b3d08d08acd53
Source dataset
uspto-grants-2011_01
Patent number
US07868185B2

Reaction notes

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