Triethylsilane → HCID 13728725, compound

HRID 256409Notes

Reaction equation

HRID 256409 reaction equation
C([SiH](CC)CC)C.[CH:8]1([CH2:14][CH:15]2[CH2:19][C:18]3[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=3[O:16]2)CCC[CH2:10][CH2:9]1>FC(F)(F)C(O)=O>[CH2:14]([CH:15]1[CH2:19][C:18]2[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=2[O:16]1)[CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 2

HCID 12052TriethylsilaneHCID 13728721HCID 13728721, compound

Product 1

HCID 13728725HCID 13728725, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Reduction of 15 g (86.0 mmole) of the above product with triethylsilane in trifluoroacetic acid by the method of Preparation D, Part (iv), and purification of the crude product on a silica gel column, eluting with hexane and hexane containing 5% ethyl acetate and distillation of the combined product fractions gave 15.5 g of the title compound as a clear oil, b.p. 114°-120° C. 15 Torr. M.S. (m/e): 176 (M+), TLC Rf 0.55, hexane.

Workup

  1. washeluting with hexane and hexane containing 5% ethyl acetate and distillation of the combined product fractions

Sources & evidence

ORD record
ord-36b04ffa5f9d4881ba0ff3aa94fad859
Source dataset
uspto-grants-1987_10
Patent number
US04703052

Reaction notes

Loading…