Ethanol → HCID 10243414, compound

HRID 256458Notes

Reaction equation

HRID 256458 reaction equation
C(=O)([O-])[O-].[Na+].[Na+].Cl.[NH2:8][OH:9].[CH3:10][C:11]1[CH:18]=[CH:17][C:14]([CH2:15]Br)=[CH:13][CH:12]=1.[CH2:19](O)[CH3:20]>CN(C)C=O>[CH3:10][C:11]1[CH:18]=[CH:17][C:14]([CH2:15][N:8]([CH2:10][C:11]2[CH:18]=[CH:17][C:19]([CH3:20])=[CH:13][CH:12]=2)[OH:9])=[CH:13][CH:12]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 7721p-Xylyl bromideHCID 10340Sodium CarbonateHCID 443297Hydroxyamine hydrochloride

Product 1

HCID 10243414HCID 10243414, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The procedure of Example 1 is repeated using 10.6 g of sodium carbonate, 1.74 g of hydroxylamine hydrochloride and 9.25 g of p-methylbenzyl bromide in 50 ml of dimethylformamide. Trituration of the crude product with ethanol affords 3.3 g of the above-named hydroxylamine as a white solid, mp 107°-109° C.

Sources & evidence

ORD record
ord-7851a5283465458ba1fbc0c8fe41aa71
Source dataset
uspto-grants-1987_10
Patent number
US04703073

Reaction notes

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