反应详情

温度

0 °C

5.10-2 mol of NaH was added little by little to a solution of 5.10-2 mol of 4-hydroxy benzonitrile in 100 ml DMF so as to obtain a temperature of 25° C. The solution was then heated to 50° C. until no more hydrogen was liberated. After cooling to 0° C., 5.10-2 benzyl chloride was added. The reaction mixture was heated to 40° C. for 1 hour, then poured into 300 ml iced water. The resulting solid was separated by filtration.

1. customto obtain a temperature of 25° C
2. temperatureThe reaction mixture was heated to 40° C. for 1 hour
3. customThe resulting solid was separated by filtration