反应详情

A solution of the product of Step E in dry tetrahydrofuran is treated protionwise with triphenylphosphine (1 equivalent). The solution is stirred under N2 at ambient temperature. After about 2 hours, when gas evolution has ceased, H2O (1 equivalent) is added, and the solution is concentrated in vacuo, and the residue is chromatographed on silica gel to give the title compound.

1. concentrationthe solution is concentrated in vacuo
2. customthe residue is chromatographed on silica gel