Tert-Butylamine → HCID 54318792, compound

HRID 259603Notes

Reaction equation

HRID 259603 reaction equation
[CH2:1]([O:3][C:4]([NH:6][CH:7]=[CH:8][C:9]1[CH:19]=[CH:18][C:12]([O:13][CH2:14][CH:15]2[O:17][CH2:16]2)=[CH:11][CH:10]=1)=[O:5])[CH3:2].[C:20]([NH2:24])([CH3:23])([CH3:22])[CH3:21]>C(O)(C)C>[C:4]([NH:6][CH:7]=[CH:8][C:9]1[CH:19]=[CH:18][C:12]([O:13][CH2:14][CH:15]([OH:17])[CH2:16][NH:24][C:20]([CH3:23])([CH3:22])[CH3:21])=[CH:11][CH:10]=1)([O:3][CH2:1][CH3:2])=[O:5]

Participants

4

Reactant 2

HCID 6385Tert-ButylamineHCID 54102988HCID 54102988, compound

Product 1

HCID 54318792HCID 54318792, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Analogously to the description in Example 2, 2.5 g (0.01 mol) of 1-[p-(2-ethoxycarbonylaminovinyl)-phenoxy]-2,3-epoxy-propane, on reaction with 1.0 ml (0.01 mol) of tert.-butylamine in 50 ml of isopropanol, yield 1-[p-(2-carbethoxyaminovinyl)-phenoxy]-2-hydroxy-3-tertiary-butylaminopropane as an oil. Its N-cyclohexyl-sulphamate, prepared in acetone, shows a melting point of 99°-100° C. (from ether).

Sources & evidence

ORD record
ord-2fdaa51bcc1e4fce9c53b97f5573e88b
Source dataset
uspto-grants-1977_07
Patent number
US04038414

Reaction notes

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