反应详情

Heptanoyl chloride was added to a suspension of aluminum chloride in dichloromethane. The mixture was stirred at room temperature for 30 minutes. To the mixture was added a solution of indole in dichloromethane. The mixture was stirred at room temperature for 1 hour and poured into a mixture of hydrochloric acid and ethyl acetate. The organic layer was washed with water, dried over magnesium sulfate and evaporated. The residue was crystallized from diisopropyl ether to give 3-heptanoylindole as a white powder.

1. stirringThe mixture was stirred at room temperature for 1 hour
2. washThe organic layer was washed with water
3. dry with materialdried over magnesium sulfate
4. customevaporated
5. customThe residue was crystallized from diisopropyl ether