反应详情

温度

0 °C

To a solution of 4-methoxybenzyl alcohol and triethylamine in dichloromethane was added 4-bromobutyryl chloride at 0° C. The mixture was stirred at 0° C. for 30 minutes, and the solvent was evaporated. The residue was diluted with ethyl acetate, and the organic solution was washed with water and brine, dried over magnesium sulfate and concentrated. The concentrate was chromatographed on a silica gel column to give the object compound.

1. customthe solvent was evaporated
2. additionThe residue was diluted with ethyl acetate
3. washthe organic solution was washed with water and brine
4. dry with materialdried over magnesium sulfate
5. concentrationconcentrated
6. customThe concentrate was chromatographed on a silica gel column
7. customto give the object compound