反应详情

A mixture of 6.9 g. 3-diallylsulphamoyl-1,2,4-triazole, 4.5 g. diethylcarbamoyl chloride, 6ml. triethylamine and 25 ml. dry tetrahydrofuran was refluxed under anhydrous conditions for 1.5 hours. The cooled reaction mixture was filtered to remove triethylamine hydrochloride and the filtrate was evaporated to remove solvent. The solid residue was recrystallized from petroleum ether, b.p. 60°-80° C., to give 1-diethylcarbamoyl-3-diallylsulphamoyl-1,2,4-triazole, m.p. 49°-51° C. Elemental analysis satisfactory.

1. additionA mixture of 6.9 g
2. customThe cooled reaction mixture
3. filtrationwas filtered
4. customto remove triethylamine hydrochloride
5. customthe filtrate was evaporated
6. customto remove solvent
7. customThe solid residue was recrystallized from petroleum ether, b.p. 60°-80° C.