Triethylamine → HCID 21318669, compound

HRID 262406Notes

Reaction equation

HRID 262406 reaction equation
Cl.[CH3:2][O:3][NH2:4].C(N(CC)CC)C.[S:12]1[CH:16]=[CH:15][C:14]2[CH2:17][CH2:18][CH2:19][CH:20]([N:21]=[C:22]=[O:23])[C:13]1=2>C(Cl)Cl>[CH3:2][O:3][NH:4][C:22]([NH:21][CH:20]1[C:13]2[S:12][CH:16]=[CH:15][C:14]=2[CH2:17][CH2:18][CH2:19]1)=[O:23]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 521874O-Methylhydroxylamine hydrochlorideHCID 21318672HCID 21318672, compound

Product 1

HCID 21318669HCID 21318669, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

A mixture of methoxyamine hydrochloride (5 g.) in 60 ml. of methylene chloride is stirred and 6 g. of triethylamine in 15 ml. of methylene chloride is added slowly. After half an hour of stirring, 5.4 g. of 4,5,6,7-tetrahydrobenzo[b]thien-7-yl isocyanate is added dropwise. The mixture is stirred at room temperature for an hour and filtered. The filter cake is washed with water and dried to afford the title compound.

Workup

  1. stirringThe mixture is stirred at room temperature for an hour
  2. filtrationfiltered
  3. washThe filter cake is washed with water
  4. customdried

Sources & evidence

ORD record
ord-9c7adfdc4e4440a7ada377d8aa9c0a3d
Source dataset
uspto-grants-1979_05
Patent number
US04154740

Reaction notes

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