Hydroxyamine hydrochloride → 1-Hydroxy-3-(4,5,6,7-tetrahydrobenzo[b]thien-4-yl)urea

HRID 263188Notes

Reaction equation

HRID 263188 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]([N:10]=[C:11]=[O:12])[CH2:7][CH2:8][CH2:9][C:2]1=2.Cl.[NH2:14][OH:15]>C(N(CC)CC)C>[OH:15][NH:14][C:11]([NH:10][CH:6]1[C:3]2[CH:4]=[CH:5][S:1][C:2]=2[CH2:9][CH2:8][CH2:7]1)=[O:12]

Participants

4

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 205373014-Isocyanato-4,5,6,7-tetrahydro-1-benzothiophene

Product 1

HCID 203489661-Hydroxy-3-(4,5,6,7-tetrahydrobenzo[b]thien-4-yl)urea

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The above compound is prepared in the manner described in Example 6, by allowing 4,5,6,7-tetrahydrobenzo[b]thien-4-yl isocyanate to react with hydroxylamine hydrochloride in the presence of triethylamine. The product melts at 158.5° C. to 160.5° C.

Workup

  1. customThe above compound is prepared in the manner

Sources & evidence

ORD record
ord-9d55d1c2b574410f9fa71b6f15058828
Source dataset
uspto-grants-1979_05
Patent number
US04156670

Reaction notes

Loading…