Triethylamine → 4,13-Di-(n-decanoyl)-1,7,10,16-tetraoxa-4,13-diazacyclooctadecane

HRID 263283Notes

Reaction equation

HRID 263283 reaction equation
[O:1]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14][NH:13][CH2:12][CH2:11][O:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.C(N([CH2:24][CH3:25])CC)C.[C:26](Cl)(=[O:36])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]>C1C=CC=CC=1>[C:26]([N:4]1[CH2:5][CH2:6][O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][N:13]([C:26](=[O:36])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:24][CH3:25])[CH2:14][CH2:15][O:16][CH2:17][CH2:18][O:1][CH2:2][CH2:3]1)(=[O:36])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 66982Decanoyl chlorideHCID 72805Diaza-18-crown-6

Product 1

HCID 5373154,13-Di-(n-decanoyl)-1,7,10,16-tetraoxa-4,13-diazacyclooctadecane

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

In a manner similar to that described in Example 5, treat the cyclic diamine obtained in Example 4 and triethylamine in anhydrous benzene with a solution of n-decanoyl chloride (capryl chloride) in anhydrous benzene. Isolate and purify the resultant product in a manner similar to that described to obtain 4,13-di-(n-decanoyl)-1,7,10,16-tetraoxa-4,13-diazacyclooctadecane.

Workup

  1. customIsolate
  2. custompurify the resultant product in a manner similar to

Sources & evidence

ORD record
ord-dd84780391b84a739b9ba73542ba3cd7
Source dataset
uspto-grants-1979_05
Patent number
US04156683

Reaction notes

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