反应详情

To a solution of dl-2-phenyl-3-t-butyl-5-hydroxymethyloxazolidine (12.05 g.) in triethylamine (120 ml.) 13 is added p-toluenesulfonylchloride (14.5 g.). After 6 days at room temperature the mixture is added to water (500 ml.) and extracted with ether (2×200 ml.). The ether solution is washed with water, dried with anhydrous magnesium sulfate and evaporated to dryness. The residue is recrystallized from hexane to afford 2-phenyl-3-t-butyl-5-p-toluenesulfonyloxymethyloxazolidine.

1. extractionextracted with ether (2×200 ml.)
2. washThe ether solution is washed with water
3. dry with materialdried with anhydrous magnesium sulfate
4. customevaporated to dryness
5. customThe residue is recrystallized from hexane