反应详情

2,6-Dimethylaniline (94.5 grams), 5-chloromethyl-1,3-dioxolane (31.8 grams), potassium carbonate (36.7 grams) and tetraethylammonium chloride (2 grams) were charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture was heated at reflux for a period of 48 hours. After this time the mixture was filtered and distilled to yield the desired product N-(1,3-dioxolan-5-ylmethyl)-2,6-dimethylaniline having a boiling point of 132°C under aspirator pressure.

1. customequipped with a mechanical stirrer
2. temperaturethermometer and reflux condenser
3. temperatureThe reaction mixture was heated
4. temperatureat reflux for a period of 48 hours
5. filtrationAfter this time the mixture was filtered
6. distillationdistilled