反应详情

2,6-Dimethyl-4-bromoaniline (0.3 mole), 5-chloromethyl-1,3-dioxolane (0.3 mole), potassium carbonate (0.3 mole) and tetraethylammonium chloride (2 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture is heated at reflux for a period of 5 hours. After this time the mixture is filtered and distilled to yield the desired product N-(1,3-dioxolan-5-ylmethyl)-2,6-dimethyl-4-bromoaniline.

1. customequipped with a mechanical stirrer
2. temperaturethermometer and reflux condenser
3. temperatureThe reaction mixture is heated
4. temperatureat reflux for a period of 5 hours
5. filtrationAfter this time the mixture is filtered
6. distillationdistilled