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HRID269651

反应详情

EQUATION

反应方程式

HRID 269651 的结构方程式

REACTANTS

反应物

2
结构：C1CCNCC1
HCID8082

Piperidine

C5H11N

结构：CC(C)(C)OC(=O)NCCC[C@@H](CNC(=O)[C@H](CCC(N)=O)NC(=O)OCC1c2ccccc2-c2ccccc21)NC(=O)OC(C)(C)C
HCID70806689

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NCCC[C@@H](CNC(=O)[C@@H](N)CCC(N)=O)NC(=O)OC(C)(C)C
HCID88986898

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

A solution of 33 mg (0.05 mmol) of 9H-fluoren-9-ylmethyl{(1S)-4-amino-1-[({(2S)-2,5-bis[(tert-butoxycarbonyl)amino]pentyl}amino)carbonyl]-4-oxobutyl}carbamate (Example 129A) in 1 ml of dimethylformamide is stirred after the addition of 4 mg (0.05 mmol) of piperidine at room temperature for 45 min. The solvent is evaporated and the crude product is reacted without further purification.

WORKUP

后处理

  1. customThe solvent is evaporated
  2. customthe crude product is reacted without further purification