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HRID273565

反应详情

EQUATION

反应方程式

HRID 273565 的结构方程式

REACTANTS

反应物

2
结构：BrCc1ccccn1
HCID564209

2-(Bromomethyl)pyridine

C6H6BrN

结构：CC(C)(C)OC(=O)N1CCN(c2ccc(NC(=O)c3ccc(-c4ccc(Cl)cc4)o3)cc2)CC1
HCID168301698

未命名化合物

PRODUCTS

生成物

2
结构：O=C(c1ccc(-c2ccc(Cl)cc2)o1)N(Cc1ccccn1)c1ccc(N2CCNCC2)cc1
HCID53475321

5-(4-Chlorophenyl)-N-[4-(1-piperazinyl)phenyl]-N-(2-pyridinylmethyl)-2-furamide

C27H25ClN4O2

收率 123%
结构：CC(C)(C)OC(=O)N1CCN(c2ccc(NC(=O)c3ccc(-c4ccc(Cl)cc4)o3)cc2)CC1
HCID168301698

未命名化合物

2 次

AUXILIARIES

试剂、催化剂与溶剂

4
结构：O=S(=O)(O)O
试剂HCID1118

Sulfuric acid

H2O4S

结构：CC(C)(C)N=P(N1CCCC1)(N1CCCC1)N1CCCC1
试剂HCID3856267

BTPP

C16H33N4P

结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

3 次

结构：COCCOCCOC
溶剂HCID8150

Diethylene glycol dimethyl ether

C6H14O3

CONDITIONS

反应条件

温度
23 °C

WORKUP

后处理

  1. additionquenched by addition of saturated aqueous NaHCO3 (2 uL) and diluted with water (1 uL) and DMSO (2 uL)
  2. additionquenched by addition of saturated aqueous NaHCO3 (2 uL) and diluted with water (1 uL) and DMSO (2 uL)
  3. additionquenched by addition of saturated aqueous NaHCO3 (2 uL) and diluted with water (1 uL) and DMSO (2 uL)
  4. additionThe reactions were further diluted to 10 mM using DMSO.