Hydrochloric Acid → N-tritylethylenediamine

HRID 277306Notes

Reaction equation

HRID 277306 reaction equation
C1C=C2C(C(O)(O)C(=O)C2=CC=1)=O.Cl.CO[C:17]1[CH:39]=[CH:38][C:20]([C:21]([NH:34][CH2:35][CH2:36][NH2:37])([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:19][CH:18]=1.COC1C=CC(C(NCCN)(C2C=CC=CC=2)C2C=CC(OC)=CC=2)=CC=1>C(Cl)Cl.CO>[C:21]([NH:34][CH2:35][CH2:36][NH2:37])([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[C:20]1[CH:38]=[CH:39][CH:17]=[CH:18][CH:19]=1

Participants

6

Reactant 4

HCID 313Hydrochloric Acid3×HCID 10236Ninhydrin3×HCID 13871404N-(4-monomethoxytrityl)ethylenediamineHCID 18314385N-(4,4'-dimethoxytrityl)ethylenediamine

Product 1

HCID 2794294N-tritylethylenediamine

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent3×

Procedure

C21H22N2 (288.42); RF=0.21 (DCM/MeOH 5:1, v/v); spot stains with ninhydrin spray or with HCl vapour); N-(4-monomethoxytrityl)ethylenediamine; C22H24N2O (332.45); RF=0.21 (DCM/MeOH 5:1, v/v); spot stains with ninhydrin spray or with HCl vapour); N-(4,4′-dimethoxytrityl)ethylenediamine; C23H26N2O2 (362.48); RF=0.22 (DCM/MeOH 5:1, v/v); spot stains with ninhydrin spray or with HCl vapour).

Sources & evidence

ORD record
ord-45976f6eee0042eead84adfd86219e10
Source dataset
uspto-grants-2002_03
Patent number
US06355726B1

Reaction notes

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