Acetate → [5-(Furan-2-yl)pyridin-3-yl]methanol

HRID 281672Notes

Reaction equation

HRID 281672 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:8][OH:9])[cH:5][n:6][cH:7]1.[C:20](=[O:21])([O-:22])[O-:23].[C:61]([O-:62])(=[O:63])[CH3:64].[C:66]([O-:67])(=[O:68])[CH3:69].[CH:26]1([P:27]([CH:28]2[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]2-[c:40]2[c:41]([O:42][CH3:43])[cH:44][cH:45][cH:46][c:47]2[O:48][CH3:49])[CH2:50][CH2:51][CH2:52][CH2:53][CH2:54]1.[Cl-:19].[Cs+:24].[Cs+:25].[Li+:18].[O:55]1[CH2:56][CH2:57][O:58][CH2:59][CH2:60]1.[Pd+2:65].[o:10]1[c:11]([B:15]([OH:16])[OH:17])[cH:12][cH:13][cH:14]1>>[c:2]1(-[c:11]2[o:10][cH:14][cH:13][cH:12]2)[cH:3][c:4]([CH2:8][OH:9])[cH:5][n:6][cH:7]1

Participants

11

Reactant 10

HCID 175Acetate2×HCID 312ChlorideHCID 19660Carbonate IonHCID 28486Lithium ionHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2734357Furan-2-boronic acidHCID 2784733(5-Bromo-3-pyridinyl)methanolHCID 112698722-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

Product 1

HCID 24729849[5-(Furan-2-yl)pyridin-3-yl]methanol

Sources & evidence

ORD record
ord-6a607eb7c37c4cd18bfaf3d2c5fc1784
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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