Hydrochloric Acid → 8-[2,6-dichloro-3-[N-(2-phthalimidoethyl)carbamoyl]benzyloxy]-2-methylquinoline

HRID 282664Notes

Reaction equation

HRID 282664 reaction equation
[C:61](=[O:62])([OH:63])[O-:64].[CH2:25]([N:26]=[C:27]=[N:28][CH2:29][CH2:30][CH2:31][N:32]([CH3:33])[CH3:34])[CH3:35].[CH3:66][N:67]([CH3:68])[CH:69]=[O:70].[Cl:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][cH:8][cH:9][c:10]3[cH:11][cH:12][c:13]([CH3:16])[n:14][c:15]23)[c:17]([Cl:24])[cH:18][cH:19][c:20]1[C:21](=[O:22])[OH:23].[ClH:46].[NH2:47][CH2:48][CH2:49][N:50]1[C:51](=[O:60])[c:52]2[c:53]([cH:56][cH:57][cH:58][cH:59]2)[C:54]1=[O:55].[Na+:65].[OH:36][n:37]1[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2[n:44][n:45]1>>[Cl:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][cH:8][cH:9][c:10]3[cH:11][cH:12][c:13]([CH3:16])[n:14][c:15]23)[c:17]([Cl:24])[cH:18][cH:19][c:20]1[C:21](=[O:23])[NH:47][CH2:48][CH2:49][N:50]1[C:51](=[O:60])[c:52]2[c:53]([cH:56][cH:57][cH:58][cH:59]2)[C:54]1=[O:55]

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 12753432-(2-Aminoethyl)-1H-isoindole-1,3(2H)-dioneHCID 183218388-(2,6-Dichloro-3-carboxybenzyloxy)-2-methylquinoline

Product 1

HCID 183218478-[2,6-dichloro-3-[N-(2-phthalimidoethyl)carbamoyl]benzyloxy]-2-methylquinoline

Sources & evidence

ORD record
ord-9e8ce67b1e22441697f0ebb0409786ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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