Chloride → Ethyl 6-[(4,4-dimethylchroman-6-yl)ethynyl]nicotinate
Reaction equation
[CH2:15]([Li:16])[CH2:17][CH2:18][CH3:19].[CH3:1][C:2]1([CH3:14])[CH2:3][CH2:4][O:5][c:6]2[cH:7][cH:8][c:9]([C:12]#[CH:13])[cH:10][c:11]21.[CH3:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37].[Cl-:43].[Cl-:45].[Cl:20][c:21]1[n:22][cH:23][c:24]([C:25](=[O:26])[O:27][CH2:28][CH3:29])[cH:30][cH:31]1.[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[Zn+2:44]>>[CH3:1][C:2]1([CH3:14])[CH2:3][CH2:4][O:5][c:6]2[cH:7][cH:8][c:9]([C:12]#[C:13][c:21]3[n:22][cH:23][c:24]([C:25](=[O:26])[O:27][CH2:28][CH3:29])[cH:30][cH:31]3)[cH:10][c:11]21Participants
8
Sources & evidence
- ORD record
- ord-17ac63f3ae254c9a9eed4c298b7b0fc5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…