Tetrahydrofuran → Hydrochloric Acid

HRID 284412Notes

Reaction equation

HRID 284412 reaction equation
[C:16]12([OH:27])[C:17]([CH3:25])([OH:26])[CH2:18][CH2:19][CH:20]([C:21]1([CH3:22])[CH3:23])[CH2:24]2.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH:9]([CH:10]([Cl:11])[B:12]([OH:13])[OH:14])[CH3:15].[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:29][Si:30]([N-:33][Si:31]([CH3:32])([CH3:34])[CH3:35])([CH3:36])[CH3:37].[Li+:28]>>[C:16]12([OH:27])[C:17]([CH3:25])([OH:26])[CH2:18][CH2:19][CH:20]([C:21]1([CH3:22])[CH3:23])[CH2:24]2.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH:9]([CH:10]([B:12]([OH:13])[OH:14])[NH2:33])[CH3:15].[ClH:11]

Participants

8

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 3280088Npc316347HCID 21922435(1-Chloro-2-phenylmethoxypropyl)boronic acidHCID 219250472,6,6-Trimethylbicyclo[3.1.1]heptane-1,2-diol

Product 3

HCID 313Hydrochloric AcidHCID 21922461(1-Amino-2-phenylmethoxypropyl)boronic acidHCID 219250472,6,6-Trimethylbicyclo[3.1.1]heptane-1,2-diol

Sources & evidence

ORD record
ord-85ed9f15a73845f48565f2b0dd0579a4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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