N-methyl-2-pyrrolidone → 3-fluoro-N-(2-hydroxy-2-phenylpentyl)-4-(2-(pyridin-2-ylamino)thiazol-5-ylthio)picolinamide
Reaction equation
[CH3:37][CH2:38][N:39]=[C:40]=[N:41][CH2:42][CH2:43][CH2:44][N:45]([CH3:46])[CH3:47].[CH3:67][N:68]1[CH2:69][CH2:70][CH2:71][C:72]1=[O:73].[CH:58]([N:59]([CH:60]([CH3:61])[CH3:62])[CH2:63][CH3:64])([CH3:65])[CH3:66].[F:14][c:15]1[c:16]([C:34](=[O:35])[OH:36])[n:17][cH:18][cH:19][c:20]1[S:21][c:22]1[cH:23][n:24][c:25]([NH:27][c:28]2[n:29][cH:30][cH:31][cH:32][cH:33]2)[s:26]1.[NH2:1][CH2:2][C:3]([CH2:4][CH2:5][CH3:6])([OH:7])[c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1.[OH:48][n:49]1[c:50]2[c:51]([cH:52][cH:53][cH:54][cH:55]2)[n:56][n:57]1>>[NH:1]([CH2:2][C:3]([CH2:4][CH2:5][CH3:6])([OH:7])[c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[C:34]([c:16]1[c:15]([F:14])[c:20]([S:21][c:22]2[cH:23][n:24][c:25]([NH:27][c:28]3[n:29][cH:30][cH:31][cH:32][cH:33]3)[s:26]2)[cH:19][cH:18][n:17]1)=[O:35]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fc50e89a683246aba492a22afecc823a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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