Hydrochloric Acid → Hydrochloric Acid

HRID 284975Notes

Reaction equation

HRID 284975 reaction equation
[CH3:3][c:4]1[n:5][c:6]2[cH:7][cH:8][cH:9][c:10]([N:14]3[CH2:15][CH2:16][N:17]([CH2:20][CH2:21][c:22]4[cH:23][c:24]([N:28]5[C:29](=[O:33])[NH:30][CH2:31][CH2:32]5)[cH:25][cH:26][cH:27]4)[CH2:18][CH2:19]3)[c:11]2[cH:12][cH:13]1.[CH3:44][OH:45].[ClH:1].[ClH:2].[H-:34].[I:36][CH2:37][CH3:38].[Na+:35].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[CH3:3][c:4]1[n:5][c:6]2[cH:7][cH:8][cH:9][c:10]([N:14]3[CH2:15][CH2:16][N:17]([CH2:20][CH2:21][c:22]4[cH:23][c:24]([N:28]5[C:29](=[O:33])[N:30]([CH2:37][CH3:38])[CH2:31][CH2:32]5)[cH:25][cH:26][cH:27]4)[CH2:18][CH2:19]3)[c:11]2[cH:12][cH:13]1.[ClH:1]

Participants

9

Reactant 7

HCID 313Hydrochloric Acid2×HCID 887MethanolHCID 923Sodium ionHCID 6228DimethylformamideHCID 6340IodoethaneHCID 166653HydrideHCID 11292933Gsk163090

Product 2

HCID 313Hydrochloric AcidHCID 574443691-Ethyl-3-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]imidazolidin-2-one

Sources & evidence

ORD record
ord-ad33b2312a5c435ea1ec344a093471d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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