Dimethylformamide → (1-Methanesulfonyl-1,2,3,4-tetrahydro-quinolin-7-yl)-[7-(6-methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-amine

HRID 285455Notes

Reaction equation

HRID 285455 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]3[cH:13][n:14][c:15]([O:18][S:19]([C:20]([F:21])([F:22])[F:23])(=[O:24])=[O:25])[n:16][n:17]23)[cH:7][n:8]1.[CH3:35][S:36](=[O:37])(=[O:38])[N:39]1[CH2:40][CH2:41][CH2:42][c:43]2[cH:44][cH:45][c:46]([NH2:49])[cH:47][c:48]21.[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[CH3:55][CH2:56][O:57][C:58]([CH3:59])=[O:60].[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]3[cH:13][n:14][c:15]([NH:49][c:46]4[cH:45][cH:44][c:43]5[c:48]([cH:47]4)[N:39]([S:36]([CH3:35])(=[O:37])=[O:38])[CH2:40][CH2:41][CH2:42]5)[n:16][n:17]23)[cH:7][n:8]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 81531DiisopropylethylamineHCID 91252911-(Methylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-amineHCID 86661684Trifluoro-methanesulfonic acid 7-(6-methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl ester

Product 1

HCID 66712559(1-Methanesulfonyl-1,2,3,4-tetrahydro-quinolin-7-yl)-[7-(6-methoxy-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-amine

Sources & evidence

ORD record
ord-a09e7986eb424a67a6632b928bd901ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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