1,2-Dichloroethane → 3-hydroxy-3-(5-hydroxy-3-methyl-1,2-benzisoxazol-6-yl)-1-(4-methoxybenzyl)-1,3-dihydro-2H-indol-2-one

HRID 285925Notes

Reaction equation

HRID 285925 reaction equation
[CH3:17][O:18][c:19]1[cH:20][cH:21][c:22]([CH2:23][N:24]2[C:25](=[O:34])[C:26](=[O:33])[c:27]3[cH:28][cH:29][cH:30][cH:31][c:32]32)[cH:35][cH:36]1.[CH3:1][c:2]1[n:3][o:4][c:5]2[c:6]1[cH:7][c:8]([OH:11])[cH:9][cH:10]2.[CH:13]([Mg+:14])([CH3:15])[CH3:16].[Cl-:12].[Cl:38][CH2:39][CH2:40][Cl:41].[ClH:37]>>[CH3:1][c:2]1[n:3][o:4][c:5]2[c:6]1[cH:7][c:8]([OH:11])[c:9]([C:26]1([OH:33])[C:25](=[O:34])[N:24]([CH2:23][c:22]3[cH:21][cH:20][c:19]([O:18][CH3:17])[cH:36][cH:35]3)[c:32]3[c:27]1[cH:28][cH:29][cH:30][cH:31]3)[cH:10]2

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 312ChlorideHCID 313Hydrochloric AcidHCID 20487021-(4-methoxybenzyl)-1H-indole-2,3-dioneHCID 226120343-Methylbenzo[d]isoxazol-5-olHCID 178461726HCID 178461726, compound

Product 1

HCID 686020023-hydroxy-3-(5-hydroxy-3-methyl-1,2-benzisoxazol-6-yl)-1-(4-methoxybenzyl)-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-e19d24d01e3345dcb555740eb0cbd234
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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