Chloride → 6-Bromo-8-chloro-4-isopropyl-7-ethoxy-2,2-dimethyl-2H-chromene

HRID 286752Notes

Reaction equation

HRID 286752 reaction equation
[Br:6][c:7]1[cH:8][c:9]2[c:14]([c:15]([Cl:20])[c:16]1[O:17][CH2:18][CH3:19])[O:13][C:12]([CH3:21])([CH3:22])[CH2:11][C:10]2=[O:23].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:24][N:25]1[CH2:26][CH2:27][CH2:28][N:29]([CH3:30])[C:31]1=[O:32].[CH:2]([CH3:3])([CH3:4])[Mg+:5].[Cl-:1]>>[CH:2]([CH3:3])([CH3:4])[C:10]1=[CH:11][C:12]([CH3:21])([CH3:22])[O:13][c:14]2[c:9]1[cH:8][c:7]([Br:6])[c:16]([O:17][CH2:18][CH3:19])[c:15]2[Cl:20]

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 816462(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-HCID 224907976-Bromo-8-chloro-7-ethoxy-2,2-dimethyl-chroman-4-oneHCID 178461726HCID 178461726, compound

Product 1

HCID 224909896-Bromo-8-chloro-4-isopropyl-7-ethoxy-2,2-dimethyl-2H-chromene

Sources & evidence

ORD record
ord-ba8c1e7d29dd48028f6f65a94897bae6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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