Hydrochloric Acid → (1-(3-fluoro-4-iodophenyl)-1H-imidazol-4-yl)methanol

HRID 287029Notes

Reaction equation

HRID 287029 reaction equation
[CH3:35][S:36]([CH3:37])=[O:38].[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[ClH:10].[Cu:39][I:40].[I:1][c:2]1[c:3]([F:9])[cH:4][c:5]([I:8])[cH:6][cH:7]1.[K+:29].[K+:30].[O-:31][C:32]([O-:33])=[O:34].[OH2:47].[OH:11][CH2:12][c:13]1[n:14][cH:15][nH:16][cH:17]1.[OH:18][c:19]1[cH:20][cH:21][cH:22][c:23]2[c:24]1[n:25][cH:26][cH:27][cH:28]2>>[I:1][c:2]1[c:3]([F:9])[cH:4][c:5](-[n:16]2[cH:15][n:14][c:13]([CH2:12][OH:11])[cH:17]2)[cH:6][cH:7]1

Participants

11

Reactant 10

HCID 313Hydrochloric AcidHCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 19238-HydroxyquinolineHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 27370962,5-DiiodofluorobenzeneHCID 178519868HCID 178519868, compound

Product 1

HCID 66974146(1-(3-fluoro-4-iodophenyl)-1H-imidazol-4-yl)methanol

Sources & evidence

ORD record
ord-4140e2c8cf6640e58b964f1631f20133
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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