1,2-Dichloroethane → 2-(2-Oxo-3-pyridin-2-ylimidazolidin-1-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl)acetamide

HRID 287055Notes

Reaction equation

HRID 287055 reaction equation
[CH2:36]([Cl:37])[CH2:38][Cl:39].[CH:50]([N:51]([CH2:52][CH3:53])[CH:54]([CH3:55])[CH3:56])([CH3:57])[CH3:58].[NH2:17][c:18]1[cH:19][c:20]2[c:24]([cH:25][cH:26]1)[CH2:23][C:22]1([CH2:21]2)[C:27](=[O:35])[NH:28][c:29]2[n:30][cH:31][cH:32][cH:33][c:34]21.[O:1]=[C:2]1[N:3]([CH2:13][C:14](=[O:15])[OH:16])[CH2:4][CH2:5][N:6]1[c:7]1[n:8][cH:9][cH:10][cH:11][cH:12]1.[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[OH:40][n:41]1[c:42]2[c:43]([cH:44][cH:45][cH:46][cH:47]2)[n:48][n:49]1>>[O:1]=[C:2]1[N:3]([CH2:13][C:14](=[O:16])[NH:17][c:18]2[cH:19][c:20]3[c:24]([cH:25][cH:26]2)[CH2:23][C:22]2([CH2:21]3)[C:27](=[O:35])[NH:28][c:29]3[n:30][cH:31][cH:32][cH:33][c:34]32)[CH2:4][CH2:5][N:6]1[c:7]1[n:8][cH:9][cH:10][cH:11][cH:12]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 184426422-oxo-3-(2-pyridinyl)-1-Imidazolidineacetic acidHCID 591667225-amino-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Product 1

HCID 116266352-(2-Oxo-3-pyridin-2-ylimidazolidin-1-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl)acetamide

Sources & evidence

ORD record
ord-32a377e443f04f92bb286703bb4dd928
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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