Hydrochloric Acid → [3-(4-chlorobenzyl)-4-difluoromethoxy-8-fluoro-2-methylquinolin-5-yloxy]acetic Acid
Reaction equation
[CH3:1][O:2][C:3]([CH2:4][O:5][c:6]1[c:7]2[c:8]([O:26][CH:27]([F:28])[F:29])[c:9]([CH2:18][c:19]3[cH:20][cH:21][c:22]([Cl:25])[cH:23][cH:24]3)[c:10]([CH3:17])[n:11][c:12]2[c:13]([F:16])[cH:14][cH:15]1)=[O:30].[CH3:31][OH:32].[ClH:35].[Li+:33].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH-:34].[OH2:41]>>[O:2]=[C:3]([CH2:4][O:5][c:6]1[c:7]2[c:8]([O:26][CH:27]([F:28])[F:29])[c:9]([CH2:18][c:19]3[cH:20][cH:21][c:22]([Cl:25])[cH:23][cH:24]3)[c:10]([CH3:17])[n:11][c:12]2[c:13]([F:16])[cH:14][cH:15]1)[OH:30]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-28647617cbaa47aea12cc951d642c268
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…