Hydrogen Bromide → 2-(4-Cyanopiperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline

HRID 288837Notes

Reaction equation

HRID 288837 reaction equation
[BrH:25].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[N:1]1([c:7]2[n:8][c:9]3[cH:10][c:11]([O:20][CH3:21])[c:12]([O:18][CH3:19])[cH:13][c:14]3[c:15]([NH2:17])[n:16]2)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[N:22]#[C:23][Br:24]>>[N:1]1([c:7]2[n:8][c:9]3[cH:10][c:11]([O:20][CH3:21])[c:12]([O:18][CH3:19])[cH:13][c:14]3[c:15]([NH2:17])[n:16]2)[CH2:2][CH2:3][N:4]([C:23]#[N:22])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 260Hydrogen BromideHCID 6228DimethylformamideHCID 10476Cyanogen BromideHCID 6162672-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline

Product 1

HCID 213933662-(4-Cyanopiperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline

Sources & evidence

ORD record
ord-a365686477024a6394b85cb37df763fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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