Chloride → Tert-butyl 7-(2-chlorophenyl)-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate

HRID 289084Notes

Reaction equation

HRID 289084 reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:37][CH2:38][O:39][C:40]([CH3:41])=[O:42].[CH:28]([Mg+:29])([CH3:30])[CH3:31].[Cl-:27].[Cl:1][c:2]1[c:3]([NH:8][CH2:9][CH2:10][C:11]2([C:23]([O:25][CH3:24])=[O:26])[N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[cH:4][cH:5][cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([N:8]2[CH2:9][CH2:10][C:11]3([N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]3)[C:23]2=[O:25])[cH:4][cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 673556421-tert-Butyl 2-methyl 2-{2-[(2-chlorophenyl)amino]ethyl}pyrrolidine-1,2-dicarboxylateHCID 178461726HCID 178461726, compound

Product 1

HCID 58948328Tert-butyl 7-(2-chlorophenyl)-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate

Sources & evidence

ORD record
ord-ed2d3786e11f41f1b56b82259b4fe581
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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