Hydrochloric Acid → Methyl 2-methyl-2-(5-methyl-6-(2,2,2-trifluoroethoxy)picolinamido)propanoate

HRID 289085Notes

Reaction equation

HRID 289085 reaction equation
[CH3:18][O:19][C:20]([C:21]([NH2:22])([CH3:23])[CH3:24])=[O:25].[CH3:1][c:2]1[cH:3][cH:4][c:5]([C:14](=[O:15])[OH:16])[n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13].[CH:50]([N:51]([CH2:52][CH3:53])[CH:54]([CH3:55])[CH3:56])([CH3:57])[CH3:58].[ClH:17].[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[P-:26]([F:27])([F:28])([F:29])([F:30])([F:31])[F:32].[n:33]1([O:34][C:35]([N:36]([CH3:37])[CH3:38])=[N+:39]([CH3:40])[CH3:41])[c:42]2[n:43][cH:44][cH:45][cH:46][c:47]2[n:48][n:49]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([C:14](=[O:16])[NH:22][C:21]([C:20]([O:19][CH3:18])=[O:25])([CH3:23])[CH3:24])[n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13]

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4186341Methyl 2-amino-2-methylpropanoateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 710875095-Methyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid

Product 1

HCID 71087523Methyl 2-methyl-2-(5-methyl-6-(2,2,2-trifluoroethoxy)picolinamido)propanoate

Sources & evidence

ORD record
ord-4bb4ccddc731453c9b64ad60ce088cfa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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