Hydrochloric Acid → 3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

HRID 290062Notes

Reaction equation

HRID 290062 reaction equation
[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[CH3:36][C:37]([O-:38])([CH3:39])[CH3:40].[CH3:48][CH2:49][O:50][C:51]([CH3:52])=[O:53].[CH3:54][CH2:55][O:56][CH2:57][CH3:58].[ClH:42].[K+:41].[NH2:1][C:2]([CH:3]([CH2:4][CH2:5][C:6]([O:8][CH3:7])=[O:9])[N:10]1[C:11](=[O:34])[c:12]2[cH:13][cH:14][cH:15][c:16]([O:19][CH2:20][c:21]3[cH:22][cH:23][c:24]([CH2:27][N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[cH:25][cH:26]3)[c:17]2[CH2:18]1)=[O:35].[Na+:47].[O-:43][C:44]([OH:45])=[O:46]>>[NH:1]1[C:2](=[O:35])[CH:3]([N:10]2[C:11](=[O:34])[c:12]3[cH:13][cH:14][cH:15][c:16]([O:19][CH2:20][c:21]4[cH:22][cH:23][c:24]([CH2:27][N:28]5[CH2:29][CH2:30][O:31][CH2:32][CH2:33]5)[cH:25][cH:26]4)[c:17]3[CH2:18]2)[CH2:4][CH2:5][C:6]1=[O:8]

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 813Potassium CationHCID 923Sodium ionHCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 45749132-Methylpropan-2-olateHCID 673340944-Carbamoyl-4-[4-(4-morpholin-4-ylmethyl-benzyloxy)-1-oxo-1,3-dihydro-isoindol-2-yl]-butyric acid methyl ester

Product 1

HCID 533280433-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Sources & evidence

ORD record
ord-9f0b0faf25d7451a9095fe4c8c611027
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…