Tetrahydrofuran → Phenylmethyl 4,4-bis(2-hydroxyethyl)-1-piperidinecarboxylate

HRID 290381Notes

Reaction equation

HRID 290381 reaction equation
[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[Cl:13][C:14](=[O:15])[O:16][CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH:1][CH2:2][CH2:3][C:4]1([CH2:10][CH2:11][OH:12])[CH2:5][CH2:6][NH:7][CH2:8][CH2:9]1>>[OH:1][CH2:2][CH2:3][C:4]1([CH2:10][CH2:11][OH:12])[CH2:5][CH2:6][N:7]([C:14](=[O:15])[O:16][CH2:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[CH2:8][CH2:9]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 10387Benzyl chloroformateHCID 22989523367282-75-5

Product 1

HCID 22989502Phenylmethyl 4,4-bis(2-hydroxyethyl)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-49f022300b954b68921d2964469a22f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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