Hydrochloric Acid → 2-({(2-(4-Chlorophenyl)-1,3-thiazol-4-yl)methyl}sulfanyl)-6-((2,2-difluoroethyl)amino)-4-(4-(2-hydroxyethoxy)phenyl)pyridine-3,5-dicarbonitrile
Reaction equation
[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[Cl:1][c:2]1[n:3][c:4]([S:22][CH2:23][c:24]2[n:25][c:26](-[c:29]3[cH:30][cH:31][c:32]([Cl:35])[cH:33][cH:34]3)[s:27][cH:28]2)[c:5]([C:20]#[N:21])[c:6](-[c:10]2[cH:11][cH:12][c:13]([O:16][CH2:17][CH2:18][OH:19])[cH:14][cH:15]2)[c:7]1[C:8]#[N:9].[ClH:36].[F:37][CH:38]([CH2:39][NH2:40])[F:41].[O:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1>>[c:2]1([NH:40][CH2:39][CH:38]([F:37])[F:41])[n:3][c:4]([S:22][CH2:23][c:24]2[n:25][c:26](-[c:29]3[cH:30][cH:31][c:32]([Cl:35])[cH:33][cH:34]3)[s:27][cH:28]2)[c:5]([C:20]#[N:21])[c:6](-[c:10]2[cH:11][cH:12][c:13]([O:16][CH2:17][CH2:18][OH:19])[cH:14][cH:15]2)[c:7]1[C:8]#[N:9]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0ba99c60d78042d2a2f92272751f7115
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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