Potassium Cation → 2-Chloro-4-cyclopropylpyrimidine

HRID 292460Notes

Reaction equation

HRID 292460 reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH:9]1([B:12]([OH:13])[OH:14])[CH2:10][CH2:11]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([Cl:8])[n:7]1.[K+:20].[K+:21].[K+:22].[P:15]([O-:16])([O-:17])([O-:18])=[O:19]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH:9]2[CH2:10][CH2:11]2)[n:7]1

Participants

6

Reactant 5

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 8028TetrahydrofuranHCID 775312,4-DichloropyrimidineHCID 2760897Cyclopropylboronic acid

Product 1

HCID 249019152-Chloro-4-cyclopropylpyrimidine

Sources & evidence

ORD record
ord-cfb53f67904c4b0a922b0e6a55a8c49f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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