Dimethylformamide → N-(3-Fluoro-4-methanesulfonylamino-benzyl)-3-(2-pyrrolidin-1-yl-6-trifluoromethyl-pyridin-3-yl)-acrylamide
Reaction equation
[CH2:35]1[CH2:36][CH2:37][NH:38][CH2:39]1.[CH3:40][CH2:41][O:42][C:43]([CH3:44])=[O:45].[Cl:1][c:2]1[n:3][c:4]([C:26]([F:27])([F:28])[F:29])[cH:5][cH:6][c:7]1[CH:8]=[CH:9][C:10](=[O:11])[NH:12][CH2:13][c:14]1[cH:15][c:16]([F:25])[c:17]([NH:20][S:21](=[O:22])(=[O:23])[CH3:24])[cH:18][cH:19]1.[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[c:2]1([N:38]2[CH2:37][CH2:36][CH2:35][CH2:39]2)[n:3][c:4]([C:26]([F:27])([F:28])[F:29])[cH:5][cH:6][c:7]1[CH:8]=[CH:9][C:10](=[O:11])[NH:12][CH2:13][c:14]1[cH:15][c:16]([F:25])[c:17]([NH:20][S:21](=[O:22])(=[O:23])[CH3:24])[cH:18][cH:19]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-aae3e7e52fb54b60893064f73c147843
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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