Hydroxide → tert-butyl N-[1-[5-chloro-3-(2-methoxypropanoylamino)-1H-pyrrolo[2,3-b]pyridin-4-yl]piperidin-3-yl]carbamate
Reaction equation
[CH3:26][O:27][CH:28]([C:29](=[O:30])[OH:31])[CH3:32].[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:43][N:44]1[CH2:45][CH2:46][CH2:47][C:48]1=[O:49].[Li+:41].[NH2:1][c:2]1[cH:3][nH:4][c:5]2[n:6][cH:7][c:8]([Cl:25])[c:9]([N:11]3[CH2:12][CH:13]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:14][CH2:15][CH2:16]3)[c:10]12.[OH-:40].[OH2:42]>>[NH:1]([c:2]1[cH:3][nH:4][c:5]2[n:6][cH:7][c:8]([Cl:25])[c:9]([N:11]3[CH2:12][CH:13]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:14][CH2:15][CH2:16]3)[c:10]12)[C:29]([CH:28]([O:27][CH3:26])[CH3:32])=[O:30]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5c81b6525e084d6c865a5a6fcf874e0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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