Hydrochloric Acid → 2-(4-Fluorophenoxy)-5-(trifluoromethyl)nicotinic acid
Reaction equation
[ClH:25].[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[c:8]([C:9](=[O:10])[O:11][CH3:12])[cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][n:16]2)[cH:21][cH:22]1.[Li+:23].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1.[O:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1.[OH-:24].[OH2:37]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[c:8]([C:9](=[O:10])[OH:11])[cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][n:16]2)[cH:21][cH:22]1Participants
8
Sources & evidence
- ORD record
- ord-722afa6b4086429cbe4832a8705b9017
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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