1,2-Dichloroethane → 5-(3-Fluoro-2-methyl-5-(1-(pyridin-2-yl)cyclopropylcarbamoyl)phenyl)-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide
Reaction equation
[CH2:52]([Cl:53])[CH2:54][Cl:55].[CH:57]([N:58]([CH:59]([CH3:60])[CH3:61])[CH2:62][CH3:63])([CH3:64])[CH3:65].[Cl:66][CH2:67][Cl:68].[ClH:56].[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][c:9](-[c:12]2[cH:13][cH:14][c:15]3[c:16]([c:17]([C:27]([NH:28][CH3:29])=[O:30])[c:18](-[c:20]4[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]4)[o:19]3)[cH:31]2)[c:10]1[CH3:11].[OH:42][n:43]1[c:44]2[c:45]([cH:46][cH:47][cH:48][cH:49]2)[n:50][n:51]1.[n:32]1[c:33]([C:38]2([NH2:41])[CH2:39][CH2:40]2)[cH:34][cH:35][cH:36][cH:37]1>>[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:41][C:38]2([c:33]3[n:32][cH:37][cH:36][cH:35][cH:34]3)[CH2:39][CH2:40]2)[cH:8][c:9](-[c:12]2[cH:13][cH:14][c:15]3[c:16]([c:17]([C:27]([NH:28][CH3:29])=[O:30])[c:18](-[c:20]4[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]4)[o:19]3)[cH:31]2)[c:10]1[CH3:11]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ce3a48420495403e8ed97e16337d18f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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