Chloride → 5-Bromo-1-methyl-3-(6-(oxetan-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-ylamino)pyridin-2(1H)-one
Reaction equation
[Br:2][c:3]1[cH:4][c:5]([NH:11][c:12]2[n:13][c:14]3[c:19]([cH:20][cH:21]2)[CH2:18][NH:17][CH2:16][CH2:15]3)[c:6](=[O:10])[n:7]([CH3:9])[cH:8]1.[C:27]([BH3-:28])#[N:29].[CH3:32][OH:33].[Cl-:34].[Cl-:36].[ClH:1].[Na+:30].[O:22]1[CH2:23][C:24](=[O:26])[CH2:25]1.[OH2:31].[Zn+2:35]>>[Br:2][c:3]1[cH:4][c:5]([NH:11][c:12]2[n:13][c:14]3[c:19]([cH:20][cH:21]2)[CH2:18][N:17]([CH:24]2[CH2:23][O:22][CH2:25]2)[CH2:16][CH2:15]3)[c:6](=[O:10])[n:7]([CH3:9])[cH:8]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-d218290d6f684cb99e96fec6ac6562e5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…