Chloride → 1-[5-(4-Methyl-5-trifluoromethyl-isoxazol-3-yl)-thiophene-2-carbonyl]piperidine-3-carboxylic acid amide
Reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[Cl-:28].[F:1][C:2]([c:3]1[c:4]([CH3:16])[c:5](-[c:8]2[cH:9][cH:10][c:11]([C:13](=[O:14])[OH:15])[s:12]2)[n:6][o:7]1)([F:17])[F:18].[NH:19]1[CH2:20][CH:21]([C:25](=[O:26])[NH2:27])[CH2:22][CH2:23][CH2:24]1>>[F:1][C:2]([c:3]1[c:4]([CH3:16])[c:5](-[c:8]2[cH:9][cH:10][c:11]([C:13](=[O:15])[N:19]3[CH2:20][CH:21]([C:25](=[O:26])[NH2:27])[CH2:22][CH2:23][CH2:24]3)[s:12]2)[n:6][o:7]1)([F:17])[F:18]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7c807b4216564409ad1540fa65e1d80d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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