Bromide ion → 2-(3,4-Difluorobenzyl)-1-(methoxycarbonyl)piperidine-4-carboxylic acid
Reaction equation
[Br-:25].[C:33]([O:34][CH3:35])([CH3:36])([CH3:37])[CH3:38].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:39][C:40]#[N:41].[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[N:7]([C:16](=[O:17])[O:18][CH3:19])[CH2:8][CH2:9][CH:10]([C:12](=[O:13])[O:14][CH3:15])[CH2:11]2)[cH:20][cH:21][c:22]1[F:23].[Li+:24].[OH2:42]>>[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[N:7]([C:16](=[O:17])[O:18][CH3:19])[CH2:8][CH2:9][CH:10]([C:12](=[O:13])[OH:14])[CH2:11]2)[cH:20][cH:21][c:22]1[F:23]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-1a2b77841b704fae8a52c95b9928b06d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…