Nitrogen → Tert-butyl 2-[[5-[2-(3-hydroxypropyl)phenyl]-3-pyridinyl]oxymethyl]azetidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:12][O:13][c:14]2[cH:15][n:16][cH:17][c:18]([Sn:20]([CH3:21])([CH3:22])[CH3:23])[cH:19]2)[CH2:10][CH2:11]1.[Cu:42][I:43].[I:24][c:25]1[c:26]([CH2:31][CH2:32][CH2:33][OH:34])[cH:27][cH:28][cH:29][cH:30]1.[N:35]#[N:36].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[cH:44]1[cH:45][cH:46][c:47]([P:48]([Pd:49]([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)([P:69]([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[P:88]([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)([c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)[c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[cH:119][cH:120]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:12][O:13][c:14]2[cH:15][n:16][cH:17][c:18](-[c:25]3[c:26]([CH2:31][CH2:32][CH2:33][OH:34])[cH:27][cH:28][cH:29][cH:30]3)[cH:19]2)[CH2:10][CH2:11]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-84d55581f04b4e56908732f57e86f17a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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