Dimethylformamide → (+/-)-3-(7-Methyl-1H-indazol-5-yl)-2-{[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidine-1-carbonyl]-amino}-propionic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([CH2:11][CH:12]([C:13](=[O:14])[OH:15])[NH:16][C:17](=[O:18])[N:19]2[CH2:20][CH2:21][CH:22]([N:25]3[C:26](=[O:35])[NH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[CH2:34]3)[CH2:23][CH2:24]2)[cH:5][c:6]2[cH:7][n:8][nH:9][c:10]12.[CH3:36][CH2:37][N:38]=[C:39]=[N:40][CH2:41][CH2:42][CH2:43][N:44]([CH3:45])[CH3:46].[CH3:56][N:57]([CH3:58])[c:59]1[cH:60][cH:61][n:62][cH:63][cH:64]1.[CH3:65][N:66]([CH3:67])[CH:68]=[O:69].[N:47]12[CH2:48][CH:49]([OH:55])[CH:50]([CH2:51][CH2:52]1)[CH2:53][CH2:54]2>>[CH3:1][c:2]1[cH:3][c:4]([CH2:11][CH:12]([C:13]([O:14][CH:49]2[CH2:48][N:47]3[CH2:52][CH2:51][CH:50]2[CH2:53][CH2:54]3)=[O:15])[NH:16][C:17](=[O:18])[N:19]2[CH2:20][CH2:21][CH:22]([N:25]3[C:26](=[O:35])[NH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[CH2:34]3)[CH2:23][CH2:24]2)[cH:5][c:6]2[cH:7][n:8][nH:9][c:10]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d8f7930dacfb45afabf187e860814204
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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