Hydrochloric Acid → [2-(2-Fluoro-phenyl)-thieno[2,3-d]pyrimidin-4-yl]-pyridin-4-yl-amine

HRID 303932Notes

Reaction equation

HRID 303932 reaction equation
[CH:32]([OH:33])([CH3:34])[CH3:35].[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6](-[c:8]3[c:9]([F:14])[cH:10][cH:11][cH:12][cH:13]3)[n:7]1)[s:15][cH:16][cH:17]2.[ClH:25].[NH2:18][c:19]1[cH:20][cH:21][n:22][cH:23][cH:24]1.[O:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1>>[c:2]1([NH:18][c:19]2[cH:20][cH:21][n:22][cH:23][cH:24]2)[c:3]2[c:4]([n:5][c:6](-[c:8]3[c:9]([F:14])[cH:10][cH:11][cH:12][cH:13]3)[n:7]1)[s:15][cH:16][cH:17]2

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 17274-AminopyridineHCID 3776IsopropanolHCID 312751,4-DioxaneHCID 211043364-Chloro-2-(2-fluorophenyl)thieno[2,3-d]pyrimidine

Product 1

HCID 21104304[2-(2-Fluoro-phenyl)-thieno[2,3-d]pyrimidin-4-yl]-pyridin-4-yl-amine

Sources & evidence

ORD record
ord-96278fd1e88043c2959b0bf8b2fd1bb2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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